5EGP

Crystal structure of the S-methyltransferase TmtA

Summary for 5EGP

Entry DOI	10.2210/pdb5egp/pdb
Descriptor	UbiE/COQ5 family methyltransferase, putative, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... (5 entities in total)
Functional Keywords	bis-thiomethyltransferase, gliotoxin, epipolythiodioxopiperazine, aspergillus fumigatus, transferase
Biological source	Aspergillus fumigatus Z5
Total number of polymer chains	2
Total formula weight	72589.76
Authors	Duell, E.R.,Glaser, M.,Antes, I.,Groll, M.,Huber, E.M. (deposition date: 2015-10-27, release date: 2016-02-03, Last modification date: 2016-04-27)
Primary citation	Duell, E.R.,Glaser, M.,Le Chapelain, C.,Antes, I.,Groll, M.,Huber, E.M. Sequential Inactivation of Gliotoxin by the S-Methyltransferase TmtA. Acs Chem.Biol., 11:1082-1089, 2016 Cited by PubMed: 26808594 DOI: 10.1021/acschembio.5b00905 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation