5EG2

SET7/9 N265A in complex with AdoHcy and TAF10 peptide

Summary for 5EG2

• Entry DOI: 10.2210/pdb5eg2/pdb
• Descriptor: Histone-lysine N-methyltransferase SETD7, Transcription initiation factor TFIID subunit 10, S-ADENOSYL-L-HOMOCYSTEINE, ... (5 entities in total)
• Functional Keywords: transferase-transcription factor complex, transferase/transcription factor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 30737.23

Authors

Kroner, G.M.,Fick, R.J.,Trievel, R.C. (deposition date: 2015-10-26, release date: 2016-01-13, Last modification date: 2023-09-27)

• Primary citation: Fick, R.J.,Kroner, G.M.,Nepal, B.,Magnani, R.,Horowitz, S.,Houtz, R.L.,Scheiner, S.,Trievel, R.C.; Sulfur-Oxygen Chalcogen Bonding Mediates AdoMet Recognition in the Lysine Methyltransferase SET7/9.; Acs Chem.Biol., 11:748-754, 2016; PubMed: 26713889; DOI: 10.1021/acschembio.5b00852

Experimental method

X-RAY DIFFRACTION (1.55 Å)