5EEI
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with SAHA
Summary for 5EEI
| Entry DOI | 10.2210/pdb5eei/pdb |
| Related | 5EDU 5EEF 5EEK 5EEM 5EEN 5EF7 5EF8 5EFB 5EFG 5EFH 5EFJ 5EFK 5EFN |
| Descriptor | Hdac6 protein, ZINC ION, POTASSIUM ION, ... (9 entities in total) |
| Functional Keywords | hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Danio rerio (Zebrafish) |
| Total number of polymer chains | 2 |
| Total formula weight | 82080.90 |
| Authors | Hai, Y.,Christianson, D.W. (deposition date: 2015-10-22, release date: 2016-07-27, Last modification date: 2023-09-27) |
| Primary citation | Hai, Y.,Christianson, D.W. Histone deacetylase 6 structure and molecular basis of catalysis and inhibition. Nat.Chem.Biol., 12:741-747, 2016 Cited by PubMed: 27454933DOI: 10.1038/nchembio.2134 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.32 Å) |
Structure validation
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