Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 2001 |
| Chain | Residue |
| A | ASP612 |
| A | HIS614 |
| A | ASP705 |
| A | SHH2004 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue K A 2002 |
| Chain | Residue |
| A | ASP610 |
| A | ASP612 |
| A | HIS614 |
| A | SER633 |
| A | LEU634 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue K A 2003 |
| Chain | Residue |
| A | PHE623 |
| A | ASP626 |
| A | VAL629 |
| A | TYR662 |
| A | HOH2239 |
| A | HOH2244 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | binding site for residue SHH A 2004 |
| Chain | Residue |
| A | PRO464 |
| A | SER531 |
| A | HIS573 |
| A | HIS574 |
| A | PHE583 |
| A | ASP612 |
| A | HIS614 |
| A | PHE643 |
| A | ASP705 |
| A | LEU712 |
| A | TYR745 |
| A | ZN2001 |
| A | GOL2005 |
| A | GOL2006 |
| A | HOH2229 |
| A | HOH2284 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 2005 |
| Chain | Residue |
| A | SHH2004 |
| A | HOH2115 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 2006 |
| Chain | Residue |
| A | ALA641 |
| A | PHE642 |
| A | PHE643 |
| A | ASN645 |
| A | SHH2004 |
| A | HOH2108 |
| A | HOH2227 |
| A | HOH2284 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 2007 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 2008 |
| Chain | Residue |
| A | ARG481 |
| A | LEU483 |
| A | SER484 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 2009 |
| Chain | Residue |
| A | ASN785 |
| A | ARG788 |
| A | HOH2277 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 2010 |
| Chain | Residue |
| A | TYR662 |
| A | PHE793 |
| A | TRP794 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 2011 |
| Chain | Residue |
| A | ARG476 |
| B | EDO809 |
| site_id | AD3 |
| Number of Residues | 14 |
| Details | binding site for residue SHH B 801 |
| Chain | Residue |
| B | PRO464 |
| B | SER531 |
| B | HIS573 |
| B | HIS574 |
| B | PHE583 |
| B | ASP612 |
| B | HIS614 |
| B | PHE643 |
| B | ASP705 |
| B | LEU712 |
| B | TYR745 |
| B | ZN802 |
| B | HOH953 |
| B | HOH1072 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 802 |
| Chain | Residue |
| B | ASP612 |
| B | HIS614 |
| B | ASP705 |
| B | SHH801 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue K B 803 |
| Chain | Residue |
| B | ASP610 |
| B | ASP612 |
| B | HIS614 |
| B | SER633 |
| B | LEU634 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue K B 804 |
| Chain | Residue |
| B | PHE623 |
| B | ASP626 |
| B | VAL629 |
| B | TYR662 |
| B | HOH967 |
| B | HOH1024 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 805 |
| Chain | Residue |
| B | ARG601 |
| B | ARG605 |
| B | GLU696 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 806 |
| Chain | Residue |
| A | ASN746 |
| A | SER749 |
| B | ARG476 |
| B | GLU479 |
| site_id | AD9 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 807 |
| site_id | AE1 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 808 |
| Chain | Residue |
| B | ARG601 |
| B | CL807 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 809 |
| Chain | Residue |
| A | ARG476 |
| A | GLU479 |
| A | CL2011 |
| B | GLY709 |
| B | ASN746 |
| B | SER749 |
