5EAL

Crystal structure of human WDR5 in complex with compound 9h

5EAL の概要

• エントリーDOI: 10.2210/pdb5eal/pdb
• 関連するPDBエントリー: 5EAM 5EAP 5EAR
• 分子名称: WD repeat-containing protein 5, 3-methyl-~{N}-[2-(4-methylpiperazin-1-yl)-5-quinolin-3-yl-phenyl]benzamide, GLYCEROL, ... (7 entities in total)
• 機能のキーワード: wdr5, compound 9h, structural genomics, structural genomics consortium, sgc, transcription-transcription inhibitor complex, transcription/transcription inhibitor
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Nucleus : P61964
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 70635.57

構造登録者

DONG, A.,DOMBROVSKI, L.,SMIL, D.,GETLIK, M.,BOLSHAN, Y.,WALKER, J.R.,SENISTERRA, G.,PODA, G.,AL-AWAR, R.,SCHAPIRA, M.,VEDADI, M.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,BROWN, P.J.,WU, H.,Structural Genomics Consortium (SGC) (登録日: 2015-10-16, 公開日: 2015-11-04, 最終更新日: 2023-09-27)

• 主引用文献: DOMBROVSKI, L.,DONG, A.,SMIL, D.,GETLIK, M.,BOLSHAN, Y.,WALKER, J.R.,SENISTERRA, G.,PODA, G.,AL-AWAR, R.,SCHAPIRA, M.,VEDADI, M.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,BROWN, P.J.,WU, H.,Structural Genomics Consortium (SGC); Crystal structure of human WDR5 in complex with compound 9h; to be published,

実験手法

X-RAY DIFFRACTION (1.8 Å)