5EA1

Crystal Structure of SMARCA4 bromodomain in complex with MPD

Summary for 5EA1

• Entry DOI: 10.2210/pdb5ea1/pdb
• Related: 5E9Y
• Descriptor: Transcription activator BRG1, (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
• Functional Keywords: four helical bundle, transcription
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : P51532
• Total number of polymer chains: 3
• Total formula weight: 47192.74

Authors

Lolli, G.,Caflisch, A. (deposition date: 2015-10-15, release date: 2016-03-16, Last modification date: 2024-01-10)

• Primary citation: Lolli, G.,Caflisch, A.; High-Throughput Fragment Docking into the BAZ2B Bromodomain: Efficient in Silico Screening for X-Ray Crystallography.; Acs Chem.Biol., 11:800-807, 2016; PubMed: 26942307; DOI: 10.1021/acschembio.5b00914

Experimental method

X-RAY DIFFRACTION (2 Å)