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5E9X

Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 2-chloro-6H-thieno[2,3-b]pyrrole-5-carboxylic acid

Summary for 5E9X
Entry DOI10.2210/pdb5e9x/pdb
DescriptorMalate synthase G, MAGNESIUM ION, 2-chloranyl-6~{H}-thieno[2,3-b]pyrrole-5-carboxylic acid, ... (4 entities in total)
Functional Keywordscomplex, transferase
Biological sourceMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Cellular locationCytoplasm : P9WK17
Total number of polymer chains1
Total formula weight80731.28
Authors
Huang, H.-L.,Sacchettini, J.C. (deposition date: 2015-10-15, release date: 2016-10-26, Last modification date: 2023-09-27)
Primary citationHuang, H.L.,Krieger, I.V.,Parai, M.K.,Gawandi, V.B.,Sacchettini, J.C.
Mycobacterium tuberculosis Malate Synthase Structures with Fragments Reveal a Portal for Substrate/Product Exchange.
J. Biol. Chem., 291:27421-27432, 2016
Cited by
PubMed: 27738104
DOI: 10.1074/jbc.M116.750877
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.943 Å)
Structure validation

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