5E9V

Crystal structure of BRD9 bromodomain in complex with an indolizine ligand

5E9V の概要

• エントリーDOI: 10.2210/pdb5e9v/pdb
• 分子名称: Bromodomain-containing protein 9, 1-[1-(imidazo[1,2-a]pyridin-5-yl)-7-(morpholin-4-yl)indolizin-3-yl]ethanone, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: bromodomain, transcription, chromatin regulation
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 29344.48

構造登録者

Tallant, C.,Hay, D.A.,Krojer, T.,Nunez-Alonso, G.,Picaud, S.,Fedorov, O.,Schofield, C.J.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Brennan, P.E.,Knapp, S. (登録日: 2015-10-15, 公開日: 2015-10-28, 最終更新日: 2024-01-10)

• 主引用文献: Tallant, C.,Hay, D.A.,Krojer, T.,Nunez-Alonso, G.,Picaud, S.,Fedorov, O.,Schofield, C.J.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Brennan, P.E.,Knapp, S.; Crystal structure of BRD9 bromodomain in complex with an indolizine ligand; To Be Published,

実験手法

X-RAY DIFFRACTION (1.8 Å)