5E9D

RD-1 Mart-1 High bound to Mart-1 decameric peptide (ELA) in complex with HLA-A2

5E9D の概要

• エントリーDOI: 10.2210/pdb5e9d/pdb
• 分子名称: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Melanoma derived Mart-1 peptide, ... (6 entities in total)
• 機能のキーワード: single chain tcr-pmhc complex, protein binding
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01892; Secreted : P61769
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 151790.60

構造登録者

Singh, N.K.,Baker, B.M. (登録日: 2015-10-15, 公開日: 2016-06-08, 最終更新日: 2023-09-27)

• 主引用文献: Harris, D.T.,Singh, N.K.,Cai, Q.,Smith, S.N.,Vander Kooi, C.W.,Procko, E.,Kranz, D.M.,Baker, B.M.; An Engineered Switch in T Cell Receptor Specificity Leads to an Unusual but Functional Binding Geometry.; Structure, 24:1142-1154, 2016; PubMed: 27238970; DOI: 10.1016/j.str.2016.04.011

実験手法

X-RAY DIFFRACTION (2.51 Å)