5E9D

RD-1 Mart-1 High bound to Mart-1 decameric peptide (ELA) in complex with HLA-A2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, F	HLA class I histocompatibility antigen, A-2 alpha chain	polymer	275	31854.2	2	UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) In PDB	Homo sapiens (Human)	MHC class I antigen A*2
2	B, G	Beta-2-microglobulin	polymer	100	11879.4	2	UniProt (P61769) Pfam (PF07654) In PDB	Homo sapiens (Human)
3	C, H	Melanoma derived Mart-1 peptide	polymer	10	985.2	2	UniProt (by SIFTS) (Q16655) In PDB	Homo sapiens
4	D, I	A6-TCR Valpha	polymer	129	14256.7	2	UniProt (A0A075B6T6) Pfam (PF07686) In PDB	Homo sapiens (Human)
5	E, J	A6-TCR Vbeta	polymer	156	16919.9	2	UniProt (A0A0K0K1A5) Pfam (PF07686) In PDB	Homo sapiens (Human)
6		water	water		18.0	73	Chemie (HOH)

Sequence modifications

B, G: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

D, I: 0 - 90 (UniProt: A0A075B6T6)

PDB	External Database	Details
Thr 30	Gln 52	engineered mutation
Ser 48	Phe 70	engineered mutation
Thr 91	-	linker
Lys 92	-	linker
Tyr 93	-	linker
Ser 94	-	linker
Trp 95	-	linker
Gly 96	-	linker
Lys 97	-	linker
Leu 98	-	linker
Gln 99	-	linker
Phe 100	-	linker
Gly 101	-	linker
Ala 102	-	linker
Gly 103	-	linker
Thr 104	-	linker
Gln 105	-	linker
Val 106	-	linker
Val 107	-	linker
Val 108	-	linker
Thr 109	-	linker
Pro 110	-	linker
Asp 111	-	linker
Gly 112	-	expression tag
Gly 113	-	expression tag
Gly 114	-	expression tag
Leu 115	-	expression tag
Asn 116	-	expression tag
Asp 117	-	expression tag
Ile 118	-	expression tag
Phe 119	-	expression tag
Glu 120	-	expression tag
Ala 121	-	expression tag
Gln 122	-	expression tag
Lys 123	-	expression tag
Ile 124	-	expression tag
Glu 125	-	expression tag
Trp 126	-	expression tag
His 127	-	expression tag
Glu 128	-	expression tag

E, J: 1 - 93 (UniProt: A0A0K0K1A5)

PDB	External Database	Details
Met -18	-	initiating methionine
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Ala 33	Ser 52	engineered mutation
Val 52	Ala 71	engineered mutation
Asp 59	Glu 78	engineered mutation
Asp 62	Asn 81	engineered mutation
Lys 65	Asn 84	engineered mutation
Arg 94	-	expression tag
Pro 95	-	expression tag
Gly 96	-	expression tag
Trp 97	-	expression tag
Met 98	-	expression tag
Ala 99	-	expression tag
Gly 100	-	expression tag
Gly 101	-	expression tag
Val 102	-	expression tag
Glu 103	-	expression tag
Leu 104	-	expression tag
Tyr 105	-	expression tag
Phe 106	-	expression tag
Gly 107	-	expression tag
Pro 108	-	expression tag
Gly 109	-	expression tag
Thr 110	-	expression tag
Arg 111	-	expression tag
Leu 112	-	expression tag
Thr 113	-	expression tag
Val 114	-	expression tag
Thr 115	-	expression tag
Glu 116	-	expression tag
Asp 117	-	expression tag
Leu 118	-	expression tag
Ile 119	-	linker
Asn 120	-	linker
Gly 121	-	linker
Ser 122	-	linker
Ala 123	-	linker
Asp 124	-	linker
Asp 125	-	linker
Ala 126	-	linker
Lys 127	-	linker
Lys 128	-	linker
Asp 129	-	linker
Ala 130	-	linker
Ala 131	-	linker
Lys 132	-	linker
Lys 133	-	linker
Asp 134	-	linker
Gly 135	-	linker
Lys 136	-	linker
Ser 137	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	151790.6
All*	Total formula weight	151790.6

*Water molecules are not included.