5E8N
The structure of the TEIPP associated Trh4 peptide in complex with H-2D(b)
Summary for 5E8N
Entry DOI | 10.2210/pdb5e8n/pdb |
Descriptor | H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, Ceramide synthase 5, ... (6 entities in total) |
Functional Keywords | cancer, neo-epitope, tap-deficiency, teipp, mhc-i, sulfur-pi interactions, non-classical peptide binding, immune system |
Biological source | Mus musculus (House Mouse) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01899 Secreted: P01887 Nucleus membrane ; Multi-pass membrane protein : Q9D6K9 |
Total number of polymer chains | 12 |
Total formula weight | 179582.05 |
Authors | Hafstrand, I.,Doorduijn, E.,Duru, A.D.,Buratto, J.,Oliveira, C.C.,Sandalova, T.,van Hall, T.,Achour, A. (deposition date: 2015-10-14, release date: 2016-02-03, Last modification date: 2024-01-10) |
Primary citation | Hafstrand, I.,Doorduijn, E.M.,Duru, A.D.,Buratto, J.,Oliveira, C.C.,Sandalova, T.,van Hall, T.,Achour, A. The MHC Class I Cancer-Associated Neoepitope Trh4 Linked with Impaired Peptide Processing Induces a Unique Noncanonical TCR Conformer. J Immunol., 196:2327-2334, 2016 Cited by PubMed: 26800871DOI: 10.4049/jimmunol.1502249 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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