5E30

Crystal structure of H5 hemagglutinin Q226L mutant from the influenza virus A/duck/Egypt/10185SS/2010 (H5N1) with LSTc

5E30 の概要

• エントリーDOI: 10.2210/pdb5e30/pdb
• 関連するPDBエントリー: 5E2Y 5E2Z 5E32 5E34 5E35
• 分子名称: Hemagglutinin, beta-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, ... (7 entities in total)
• 機能のキーワード: h5n1 influenza virus, hemagglutinin, receptor binding specificity, transmission, glycan complex, viral protein
• 由来する生物種: Influenza A virus; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 180381.26

構造登録者

Zhu, X.,Wilson, I.A. (登録日: 2015-10-01, 公開日: 2015-12-02, 最終更新日: 2023-09-27)

• 主引用文献: Zhu, X.,Viswanathan, K.,Raman, R.,Yu, W.,Sasisekharan, R.,Wilson, I.A.; Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.; Cell Rep, 13:1683-1691, 2015; PubMed: 26586437; DOI: 10.1016/j.celrep.2015.10.027

実験手法

X-RAY DIFFRACTION (2.7 Å)