5DTS

Fragments bound to the OXA-48 beta-lactamase: Compound 2

Summary for 5DTS

Entry DOI	10.2210/pdb5dts/pdb
Related	5DVA
Descriptor	Beta-lactamase, 3-(pyridin-3-yl)benzoic acid, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	inhibitor, complex, fragment, lactamase, hydrolase
Biological source	Klebsiella pneumoniae
Total number of polymer chains	4
Total formula weight	114059.84
Authors	Lund, B.A.,Christopeit, T.,Leiros, H.-K.S. (deposition date: 2015-09-18, release date: 2016-05-25, Last modification date: 2024-01-10)
Primary citation	Lund, B.A.,Christopeit, T.,Guttormsen, Y.,Bayer, A.,Leiros, H.K. Screening and Design of Inhibitor Scaffolds for the Antibiotic Resistance Oxacillinase-48 (OXA-48) through Surface Plasmon Resonance Screening. J.Med.Chem., 59:5542-5554, 2016 Cited by PubMed: 27165692 DOI: 10.1021/acs.jmedchem.6b00660 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.94015871727 Å)

Structure validation