5DVA
Fragments bound to the OXA-48 beta-lactamase: Compound 1
Summary for 5DVA
Entry DOI | 10.2210/pdb5dva/pdb |
Related | 4s2p |
Descriptor | Beta-lactamase, 3-(pyridin-4-yl)benzoic acid, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | hydrolase, inhibitor, complex, fragment, lactamase |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 4 |
Total formula weight | 114059.84 |
Authors | Lund, B.A.,Christopeit, T.,Leiros, H.-K.S. (deposition date: 2015-09-21, release date: 2016-06-01, Last modification date: 2024-01-10) |
Primary citation | Lund, B.A.,Christopeit, T.,Guttormsen, Y.,Bayer, A.,Leiros, H.K. Screening and Design of Inhibitor Scaffolds for the Antibiotic Resistance Oxacillinase-48 (OXA-48) through Surface Plasmon Resonance Screening. J.Med.Chem., 59:5542-5554, 2016 Cited by PubMed: 27165692DOI: 10.1021/acs.jmedchem.6b00660 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.50003891197 Å) |
Structure validation
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