5DSE
Crystal Structure of the TTC7B/Hyccin Complex
Summary for 5DSE
Entry DOI | 10.2210/pdb5dse/pdb |
Related | 4N5C |
Descriptor | Tetratricopeptide repeat protein 7B, Hyccin (3 entities in total) |
Functional Keywords | pi4p synthesis, protein binding |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm, cytosol : Q86TV6 Q9BYI3 |
Total number of polymer chains | 4 |
Total formula weight | 257160.85 |
Authors | Wu, X.,Baskin, J.M.,Reinisch, K.M.,De Camilli, P. (deposition date: 2015-09-17, release date: 2015-12-02, Last modification date: 2023-12-27) |
Primary citation | Baskin, J.M.,Wu, X.,Christiano, R.,Oh, M.S.,Schauder, C.M.,Gazzerro, E.,Messa, M.,Baldassari, S.,Assereto, S.,Biancheri, R.,Zara, F.,Minetti, C.,Raimondi, A.,Simons, M.,Walther, T.C.,Reinisch, K.M.,De Camilli, P. The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane. Nat.Cell Biol., 18:132-138, 2016 Cited by PubMed: 26571211DOI: 10.1038/ncb3271 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
Download full validation report