5DOY
Crystal structure of the Thermus thermophilus 70S ribosome in complex with antibiotic Hygromycin A, mRNA and three tRNAs in the A, P and E sites at 2.6A resolution
This is a non-PDB format compatible entry.
Replaces: 4Z3QSummary for 5DOY
Entry DOI | 10.2210/pdb5doy/pdb |
Related | 4Z3S 5DOX |
Descriptor | 23S Ribosomal RNA, 50S Ribosomal Protein L14, 50S Ribosomal Protein L15, ... (62 entities in total) |
Functional Keywords | hygromycin a, a201a, antibiotic, 70s ribosome, inhibition of translation, peptidyl transferase inhibitors, trna accommodation intermediate, single-molecule fret, ribosome-antibiotic complex, ribosome/antibiotic |
Biological source | Escherichia coli More |
Total number of polymer chains | 112 |
Total formula weight | 4561674.42 |
Authors | Polikanov, Y.S.,Starosta, A.L.,Juette, M.F.,Altman, R.B.,Terry, D.S.,Lu, W.,Burnett, B.J.,Dinos, G.,Reynolds, K.,Blanchard, S.C.,Steitz, T.A.,Wilson, D.N. (deposition date: 2015-09-11, release date: 2015-12-30, Last modification date: 2023-11-15) |
Primary citation | Polikanov, Y.S.,Starosta, A.L.,Juette, M.F.,Altman, R.B.,Terry, D.S.,Lu, W.,Burnett, B.J.,Dinos, G.,Reynolds, K.A.,Blanchard, S.C.,Steitz, T.A.,Wilson, D.N. Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A. Mol.Cell, 58:832-844, 2015 Cited by PubMed: 26028538DOI: 10.1016/j.molcel.2015.04.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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