5DNX

Crystal structure of IGPD from Pyrococcus furiosus in complex with (R)-C348

Summary for 5DNX

• Entry DOI: 10.2210/pdb5dnx/pdb
• Related: 5DNL
• Descriptor: Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION, [(2R)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]phosphonic acid, ... (4 entities in total)
• Functional Keywords: inhibitor, complex, dehydratase, lyase, cytoplasmic
• Biological source: Pyrococcus furiosus
• Cellular location: Cytoplasm : P58880
• Total number of polymer chains: 3
• Total formula weight: 60245.42

Authors

Bisson, C.,Britton, K.L.,Sedelnikova, S.E.,Rodgers, H.F.,Eadsforth, T.C.,Viner, R.C.,Hawkes, T.R.,Baker, P.J.,Rice, D.W. (deposition date: 2015-09-10, release date: 2016-10-05, Last modification date: 2016-10-26)

• Primary citation: Bisson, C.,Britton, K.L.,Sedelnikova, S.E.,Rodgers, H.F.,Eadsforth, T.C.,Viner, R.C.,Hawkes, T.R.,Baker, P.J.,Rice, D.W.; Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide.; Angew.Chem.Int.Ed.Engl., 55:13485-13489, 2016; PubMed: 27717128; DOI: 10.1002/anie.201607185

Experimental method

X-RAY DIFFRACTION (1.8 Å)