5DNF
Crystal structure of CC chemokine 5 (CCL5) oligomer in complex with heparin
Summary for 5DNF
Entry DOI | 10.2210/pdb5dnf/pdb |
Related | 5CMD 5COY |
Descriptor | C-C motif chemokine 5, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, alpha-D-galactopyranose, ... (8 entities in total) |
Functional Keywords | cc chemokine, high oligomer, cytokine |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 9 |
Total formula weight | 73675.35 |
Authors | Liang, W.G.,Tang, W. (deposition date: 2015-09-10, release date: 2016-04-13, Last modification date: 2020-07-29) |
Primary citation | Liang, W.G.,Triandafillou, C.G.,Huang, T.Y.,Zulueta, M.M.,Banerjee, S.,Dinner, A.R.,Hung, S.C.,Tang, W.J. Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3. Proc.Natl.Acad.Sci.USA, 113:5000-5005, 2016 Cited by PubMed: 27091995DOI: 10.1073/pnas.1523981113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.549 Å) |
Structure validation
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