5DMG

X-RAY STRUCTURE OF THE FAB FRAGMENT OF THE ANTI TAU ANTIBODY RB86 IN COMPLEX WITH THE PHOSPHORYLATED TAU PEPTIDE (416-430)

Summary for 5DMG

• Entry DOI: 10.2210/pdb5dmg/pdb
• Descriptor: RB86 antibody Fab fragment heavy chain, RB86 antibody Fab fragment light chain, Microtubule-associated protein, ... (4 entities in total)
• Functional Keywords: antibody, fab fragment, tau protein, tau-pser422, tau-pser422 complex, immune system
• Biological source: Oryctolagus cuniculus (rabbit); More
• Cellular location: Cytoplasm, cytoskeleton: B4DSE3
• Total number of polymer chains: 9
• Total formula weight: 141523.78

Authors

Benz, J.,Lorenz, S.,Georges, G.,Jochner, A.,Goepfert, U.,Grueninger, F.,Bujotzek, A. (deposition date: 2015-09-08, release date: 2015-12-16, Last modification date: 2016-03-02)

• Primary citation: Bujotzek, A.,Lipsmeier, F.,Harris, S.F.,Benz, J.,Kuglstatter, A.,Georges, G.; VH-VL orientation prediction for antibody humanization candidate selection: A case study.; Mabs, 8:288-305, 2016; PubMed: 26637054; DOI: 10.1080/19420862.2015.1117720

Experimental method

X-RAY DIFFRACTION (2.5 Å)