5DLP

Acetylcholinesterase Methylene Blue no PEG

Summary for 5DLP

• Entry DOI: 10.2210/pdb5dlp/pdb
• Related: 1W6R 2W9I
• Descriptor: Acetylcholinesterase, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: inhibitor, hydrolase
• Biological source: Torpedo californica (Pacific electric ray)
• Total number of polymer chains: 1
• Total formula weight: 64549.81

Authors

Dym, O. (deposition date: 2015-09-07, release date: 2016-03-30, Last modification date: 2024-01-10)

• Primary citation: Dym, O.,Song, W.,Felder, C.,Roth, E.,Shnyrov, V.,Ashani, Y.,Xu, Y.,Joosten, R.P.,Weiner, L.,Sussman, J.L.,Silman, I.; The impact of crystallization conditions on structure-based drug design: A case study on the methylene blue/acetylcholinesterase complex.; Protein Sci., 25:1096-1114, 2016; PubMed: 26990888; DOI: 10.1002/pro.2923

Experimental method

X-RAY DIFFRACTION (2.7 Å)