5DJ4
Leucine-bound Sestrin2 from Homo sapiens
Summary for 5DJ4
Entry DOI | 10.2210/pdb5dj4/pdb |
Descriptor | Sestrin-2, LEUCINE (3 entities in total) |
Functional Keywords | mtor, leucine, amino-acid, sensing, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 5 |
Total formula weight | 273458.70 |
Authors | Saxton, R.A.,Knockenhauer, K.E.,Schwartz, T.U. (deposition date: 2015-09-01, release date: 2015-11-25, Last modification date: 2024-03-06) |
Primary citation | Saxton, R.A.,Knockenhauer, K.E.,Wolfson, R.L.,Chantranupong, L.,Pacold, M.E.,Wang, T.,Schwartz, T.U.,Sabatini, D.M. Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway. Science, 351:53-58, 2016 Cited by PubMed: 26586190DOI: 10.1126/science.aad2087 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.697 Å) |
Structure validation
Download full validation report