5DI4
Two divalent metal ions and conformational changes play roles in the hammerhead ribozyme cleavage reaction-WT ribozyme in Mn2+ at low pH
Summary for 5DI4
Entry DOI | 10.2210/pdb5di4/pdb |
Related | 5DH6 5DH7 5DH8 5DI2 |
Descriptor | RNA (48-MER), 5'-R(*GP*GP*GP*CP*GP*U)-D(P*C)-R(P*UP*GP*GP*GP*CP*AP*GP*UP*AP*CP*CP*CP*A)-3', MANGANESE (II) ION (3 entities in total) |
Functional Keywords | ribozyme, hammerhead, rna |
Biological source | synthetic construct More |
Total number of polymer chains | 2 |
Total formula weight | 22542.50 |
Authors | Mir, A.,Chen, J.,Neau, D.,Golden, B.L. (deposition date: 2015-08-31, release date: 2015-10-07, Last modification date: 2024-03-06) |
Primary citation | Mir, A.,Chen, J.,Robinson, K.,Lendy, E.,Goodman, J.,Neau, D.,Golden, B.L. Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction. Biochemistry, 54:6369-6381, 2015 Cited by PubMed: 26398724DOI: 10.1021/acs.biochem.5b00824 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.948 Å) |
Structure validation
Download full validation report