5DH7
Two divalent metal ions and conformational changes play roles in the hammerhead ribozyme cleavage reaction-G12A mutant in Mn2+
Summary for 5DH7
Entry DOI | 10.2210/pdb5dh7/pdb |
Related | 5DH6 5DH8 5DI2 5DI4 |
Descriptor | RNA (48-MER), 5'-R(*GP*GP*GP*CP*GP*UP*DC*UP*GP*GP*GP*CP*AP*GP*UP*AP*CP*CP*CP*A)-3', MANGANESE (II) ION (3 entities in total) |
Functional Keywords | ribozyme, hammerhead, rna |
Biological source | synthetic construct More |
Total number of polymer chains | 2 |
Total formula weight | 22526.50 |
Authors | Mir, A.,Chen, J.,Neau, D.,Golden, B.L. (deposition date: 2015-08-29, release date: 2015-10-07, Last modification date: 2024-03-06) |
Primary citation | Mir, A.,Chen, J.,Robinson, K.,Lendy, E.,Goodman, J.,Neau, D.,Golden, B.L. Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction. Biochemistry, 54:6369-6381, 2015 Cited by PubMed: 26398724DOI: 10.1021/acs.biochem.5b00824 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.064 Å) |
Structure validation
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