5DGH

Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with AMP-PNP and 5-(PCP)-IP5

5DGH の概要

• エントリーDOI: 10.2210/pdb5dgh/pdb
• 関連するPDBエントリー: 5DGI
• 分子名称: Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Methylenebisphosphonate inositol pentakisphosphate, ... (7 entities in total)
• 機能のキーワード: transferase inositol diphosphoinositol pentakisphosphate kinase analog methylenebisphosphonate ppip5k atp-grasp pyrophosphate diphosphate, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39425.15

構造登録者

Wang, H.,Shears, S.B. (登録日: 2015-08-27, 公開日: 2016-08-10, 最終更新日: 2023-09-27)

• 主引用文献: Hager, A.,Wu, M.,Wang, H.,Brown, N.W.,Shears, S.B.,Veiga, N.,Fiedler, D.; Cellular Cations Control Conformational Switching of Inositol Pyrophosphate Analogues.; Chemistry, 22:12406-12414, 2016; PubMed: 27460418; DOI: 10.1002/chem.201601754

実験手法

X-RAY DIFFRACTION (2.1 Å)