5DG7
CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING dTTP ACROSS A DNA TEMPLATE CONTAINING 1,N6-ETHENODEOXYADENOSINE LESION
Summary for 5DG7
Entry DOI | 10.2210/pdb5dg7/pdb |
Related | 5DG8 5DG9 5DGA 5DGB |
Descriptor | DNA polymerase eta, DNA (5'-D(*CP*AP*TP*(EDA)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... (7 entities in total) |
Functional Keywords | dna polymerase, dna enzyme, dna damage, translesion dna synthesis, etheno dna adducts, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 55369.17 |
Authors | |
Primary citation | Patra, A.,Su, Y.,Zhang, Q.,Johnson, K.M.,Guengerich, F.P.,Egli, M. Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase eta. J.Biol.Chem., 291:14134-14145, 2016 Cited by PubMed: 27226627DOI: 10.1074/jbc.M116.732487 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.26 Å) |
Structure validation
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