5DF8
CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH CEFOPERAZONE
Summary for 5DF8
Entry DOI | 10.2210/pdb5df8/pdb |
Related | 5DF7 |
Descriptor | Cell division protein, (2R,4R,5R)-2-[(1R)-1-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoethyl]-5-methyl-1,3-thiazinane-4-carboxylic acid, GLYCEROL, ... (5 entities in total) |
Functional Keywords | cefoperazone, beta-lactam antibiotics, acyl-enzyme complex, de-acylation, transferase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 124141.60 |
Authors | Ren, J.,Nettleship, J.E.,Males, A.,Stuart, D.I.,Owens, R.J. (deposition date: 2015-08-26, release date: 2016-01-13) |
Primary citation | Ren, J.,Nettleship, J.E.,Males, A.,Stuart, D.I.,Owens, R.J. Crystal structures of penicillin-binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms. Febs Lett., 590:288-297, 2016 Cited by PubMed: 26823174DOI: 10.1002/1873-3468.12054 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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