5DF1

Iridoid synthase from Catharanthus roseus - ternary complex with NADP+ and geranic acid

5DF1 の概要

• エントリーDOI: 10.2210/pdb5df1/pdb
• 分子名称: Iridoid synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (2E)-3,7-dimethylocta-2,6-dienoic acid, ... (6 entities in total)
• 機能のキーワード: oxidoreductase, iridoid synthase, short chain dehydrogenase, nadph-dependent, catharanthus roseus
• 由来する生物種: Catharanthus roseus (Madagascar periwinkle)
• 細胞内の位置: Cytoplasm, cytosol : K7WDL7
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 85051.78

構造登録者

Caputi, L.,Kries, H.,Stevenson, C.E.M.,Kamileen, M.O.,Sherden, N.H.,Geu-Flores, F.,Lawson, D.M.,O'Connor, S.E. (登録日: 2015-08-26, 公開日: 2015-10-28, 最終更新日: 2024-01-10)

• 主引用文献: Kries, H.,Caputi, L.,Stevenson, C.E.,Kamileen, M.O.,Sherden, N.H.,Geu-Flores, F.,Lawson, D.M.,O'Connor, S.E.; Structural determinants of reductive terpene cyclization in iridoid biosynthesis.; Nat.Chem.Biol., 12:6-8, 2016; PubMed: 26551396; DOI: 10.1038/nchembio.1955

実験手法

X-RAY DIFFRACTION (1.75 Å)