5DEU
Crystal structure of TET2-5hmC complex
Summary for 5DEU
Entry DOI | 10.2210/pdb5deu/pdb |
Related | 5D9Y |
Descriptor | Methylcytosine dioxygenase TET2, chimeric construct, DNA (5'-D(*AP*CP*CP*AP*CP*(5HC)P*GP*GP*TP*GP*GP*T)-3'), DNA (5'-D(P*CP*CP*AP*CP*(5HC)P*GP*GP*TP*GP*GP*T)-3'), ... (9 entities in total) |
Functional Keywords | 5-methylcytosine dioxygenase, tet2, 5hmc, protein-dna complex, oxidoreductase-dna complex, oxidoreductase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 59100.83 |
Authors | |
Primary citation | Hu, L.,Lu, J.,Cheng, J.,Rao, Q.,Li, Z.,Hou, H.,Lou, Z.,Zhang, L.,Li, W.,Gong, W.,Liu, M.,Sun, C.,Yin, X.,Li, J.,Tan, X.,Wang, P.,Wang, Y.,Fang, D.,Cui, Q.,Yang, P.,He, C.,Jiang, H.,Luo, C.,Xu, Y. Structural insight into substrate preference for TET-mediated oxidation. Nature, 527:118-122, 2015 Cited by PubMed: 26524525DOI: 10.1038/nature15713 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.801 Å) |
Structure validation
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