5DER
RNA oligonucleotide containing (R)-C5'-ME-2'F U
Summary for 5DER
Entry DOI | 10.2210/pdb5der/pdb |
Related | 5DEK |
Descriptor | RNA oligonucleotide containing (R)-C5'-Me-2'-FU (2 entities in total) |
Functional Keywords | rna, oligonucleotide |
Biological source | synthetic construct |
Total number of polymer chains | 4 |
Total formula weight | 10170.32 |
Authors | Harp, J.M.,Egli, M. (deposition date: 2015-08-25, release date: 2016-06-29, Last modification date: 2024-03-06) |
Primary citation | Kel In, A.V.,Zlatev, I.,Harp, J.,Jayaraman, M.,Bisbe, A.,O Shea, J.,Taneja, N.,Manoharan, R.M.,Khan, S.,Charisse, K.,Maier, M.A.,Egli, M.,Rajeev, K.G.,Manoharan, M. Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5'-C-Methyl Pyrimidine-Modified Oligonucleotides. J.Org.Chem., 81:2261-2279, 2016 Cited by PubMed: 26940174DOI: 10.1021/acs.joc.5b02375 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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