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5DEB

2009 H1N1 PA endonuclease mutant E119D in complex with rUMP

Summary for 5DEB
Entry DOI10.2210/pdb5deb/pdb
Related5CCY 5CGV 5CL0 5CZN 5D2O 5D42 5D4G 5D9J 5DBS 5DBU 5DES
DescriptorPolymerase acidic protein, MANGANESE (II) ION, URIDINE-5'-MONOPHOSPHATE, ... (4 entities in total)
Functional Keywordsinfluenza, resistance, endonuclease inhibitor, viral protein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceInfluenza A virus
More
Total number of polymer chains1
Total formula weight23568.37
Authors
Kumar, G.,White, S.W. (deposition date: 2015-08-25, release date: 2016-03-16, Last modification date: 2023-09-27)
Primary citationSong, M.S.,Kumar, G.,Shadrick, W.R.,Zhou, W.,Jeevan, T.,Li, Z.,Slavish, P.J.,Fabrizio, T.P.,Yoon, S.W.,Webb, T.R.,Webby, R.J.,White, S.W.
Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113:3669-3674, 2016
Cited by
PubMed: 26976575
DOI: 10.1073/pnas.1519772113
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.14 Å)
Structure validation

217705

數據於2024-03-27公開中

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