5DE8

Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA, iridium hexammine bound form.

5DE8 の概要

• エントリーDOI: 10.2210/pdb5de8/pdb
• 分子名称: sc1, Fragile X mental retardation protein 1, POTASSIUM ION, ... (4 entities in total)
• 機能のキーワード: fragile x syndrome, rna structure, rgg box, fmrp, g-quadruplex, rna binding protein-rna complex, rna binding protein/rna
• 由来する生物種: synthetic construct; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 28047.72

構造登録者

Vasilyev, N.,Polonskaia, A.,Darnell, J.C.,Darnell, R.B.,Patel, D.J.,Serganov, A. (登録日: 2015-08-25, 公開日: 2015-09-23, 最終更新日: 2024-03-06)

• 主引用文献: Vasilyev, N.,Polonskaia, A.,Darnell, J.C.,Darnell, R.B.,Patel, D.J.,Serganov, A.; Crystal structure reveals specific recognition of a G-quadruplex RNA by a beta-turn in the RGG motif of FMRP.; Proc.Natl.Acad.Sci.USA, 112:E5391-E5400, 2015; PubMed: 26374839; DOI: 10.1073/pnas.1515737112

実験手法

X-RAY DIFFRACTION (3.1003 Å)