5DCA
Crystal structure of yeast full length Brr2 in complex with Prp8 Jab1 domain
Summary for 5DCA
Entry DOI | 10.2210/pdb5dca/pdb |
Descriptor | Pre-mRNA-splicing helicase BRR2, Pre-mRNA-splicing factor 8 (3 entities in total) |
Functional Keywords | protein complex, helicase, rnp remodeling, spliceosome activation, hydrolase |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More |
Cellular location | Nucleus : P32639 P33334 |
Total number of polymer chains | 2 |
Total formula weight | 250657.74 |
Authors | Absmeier, E.,Wollenhaupt, J.,Santos, K.F.,Wahl, M.C. (deposition date: 2015-08-23, release date: 2015-12-16, Last modification date: 2024-01-10) |
Primary citation | Absmeier, E.,Wollenhaupt, J.,Mozaffari-Jovin, S.,Becke, C.,Lee, C.T.,Preussner, M.,Heyd, F.,Urlaub, H.,Luhrmann, R.,Santos, K.F.,Wahl, M.C. The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation. Genes Dev., 29:2576-2587, 2015 Cited by PubMed: 26637280DOI: 10.1101/gad.271528.115 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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