5DBR

Ca2+ CaM with human cardiac Na+ channel (NaV1.5) inactivation gate

5DBR の概要

• エントリーDOI: 10.2210/pdb5dbr/pdb
• 分子名称: Calmodulin, Sodium channel protein type 5 subunit alpha, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: calmodulin, nav1.5, inactivation gate, metal binding protein-transport protein complex, metal binding protein/transport protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 22466.26

構造登録者

Johnson, C.N.,Thompson, M.K.,Chazin, W.J. (登録日: 2015-08-21, 公開日: 2017-02-22, 最終更新日: 2023-09-27)

• 主引用文献: Johnson, C.N.,Thompson, M.K.,Voehler, M.,Chazin, W.J.; Enhanced Understanding of Ca2+ Modulation of the Human Cardiac Sodium Channel: Tight Binding of Calmodulin to the Inactivation Gate; To Be Published,

実験手法

X-RAY DIFFRACTION (2.25 Å)