5DAH
Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide
Summary for 5DAH
Entry DOI | 10.2210/pdb5dah/pdb |
Related | 5DAG |
Descriptor | Protein AF-10, Histone H3 peptide, ZINC ION, ... (5 entities in total) |
Functional Keywords | phd finger, histone tail reader, epigenetics, h3k27 recognition, peptide binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 49277.41 |
Authors | Chen, S.,Patel, D.J. (deposition date: 2015-08-19, release date: 2015-10-21, Last modification date: 2024-03-06) |
Primary citation | Chen, S.,Yang, Z.,Wilkinson, A.W.,Deshpande, A.J.,Sidoli, S.,Krajewski, K.,Strahl, B.D.,Garcia, B.A.,Armstrong, S.A.,Patel, D.J.,Gozani, O. The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79. Mol.Cell, 60:319-327, 2015 Cited by PubMed: 26439302DOI: 10.1016/j.molcel.2015.08.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.611 Å) |
Structure validation
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