5D9H

Crystal structure of SPAK (STK39) dimer in the basal activity state

Summary for 5D9H

• Entry DOI: 10.2210/pdb5d9h/pdb
• Descriptor: STE20/SPS1-related proline-alanine-rich protein kinase, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: kinase, ste20, hypertension, stk39, transferase
• Biological source: Mus musculus (Mouse)
• Total number of polymer chains: 2
• Total formula weight: 79909.78

Authors

Taylor, C.A.,Juang, Y.C.,Goldsmith, E.J.,Cobb, M.H. (deposition date: 2015-08-18, release date: 2015-09-02, Last modification date: 2024-03-06)

• Primary citation: Taylor, C.A.,Juang, Y.C.,Earnest, S.,Sengupta, S.,Goldsmith, E.J.,Cobb, M.H.; Domain-Swapping Switch Point in Ste20 Protein Kinase SPAK.; Biochemistry, 54:5063-5071, 2015; PubMed: 26208601; DOI: 10.1021/acs.biochem.5b00593

Experimental method

X-RAY DIFFRACTION (3.1 Å)