5D8C
Crystal structure of HiNmlR, a MerR family regulator lacking the sensor domain, bound to promoter DNA
Summary for 5D8C
Entry DOI | 10.2210/pdb5d8c/pdb |
Descriptor | MerR family regulator protein, DNA (5'-D(*CP*TP*TP*AP*GP*AP*GP*TP*TP*CP*AP*CP*TP*CP*TP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*AP*GP*AP*GP*TP*GP*AP*AP*CP*TP*CP*TP*AP*AP*G)-3'), ... (4 entities in total) |
Functional Keywords | transcription factor, merr, thiol-based genetic switch, dna untwisting, transcription-dna complex, transcription/dna |
Biological source | Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) More |
Total number of polymer chains | 4 |
Total formula weight | 42404.27 |
Authors | Counago, R.M.,Chang, C.W.,Chen, N.H.,Djoko, K.Y.,McEwan, A.G.,Kobe, B. (deposition date: 2015-08-17, release date: 2016-06-29, Last modification date: 2023-09-27) |
Primary citation | Counago, R.M.,Chen, N.H.,Chang, C.W.,Djoko, K.Y.,McEwan, A.G.,Kobe, B. Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region. Nucleic Acids Res., 44:6981-6993, 2016 Cited by PubMed: 27307602DOI: 10.1093/nar/gkw543 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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