5D6W

Crystal structure of double tudor domain of human lysine demethylase KDM4A

Summary for 5D6W

Entry DOI	10.2210/pdb5d6w/pdb
Related	5D6X 5D6Y
Descriptor	Lysine-specific demethylase 4A, S,R MESO-TARTARIC ACID (3 entities in total)
Functional Keywords	double tudor domain, reader domain, structural genomics, psi-2, protein structure initiative, enzyme discovery for natural product biosynthesis, natpro, oxidoreductase
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	55508.87
Authors	Wang, F.,Su, Z.,Denu, J.M.,Phillips Jr., G.N.,Enzyme Discovery for Natural Product Biosynthesis (NatPro) (deposition date: 2015-08-13, release date: 2015-11-25, Last modification date: 2024-03-06)
Primary citation	Su, Z.,Wang, F.,Lee, J.H.,Stephens, K.E.,Papazyan, R.,Voronina, E.,Krautkramer, K.A.,Raman, A.,Thorpe, J.J.,Boersma, M.D.,Kuznetsov, V.I.,Miller, M.D.,Taverna, S.D.,Phillips, G.N.,Denu, J.M. Reader domain specificity and lysine demethylase-4 family function. Nat Commun, 7:13387-13387, 2016 Cited by PubMed: 27841353 DOI: 10.1038/ncomms13387 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.992 Å)

Structure validation