5D4G

2009 H1N1 PA endonuclease mutant F105S in complex with rUMP

Summary for 5D4G

• Entry DOI: 10.2210/pdb5d4g/pdb
• Related: 5CCY 5CGV 5CL0 5CZN 5D42
• Descriptor: Polymerase acidic protein, MANGANESE (II) ION, URIDINE-5'-MONOPHOSPHATE, ... (4 entities in total)
• Functional Keywords: influenza, resistance, endonuclease inhibitor, viral protein, hydrolase
• Biological source: Influenza A virus
• Total number of polymer chains: 1
• Total formula weight: 22344.12

Authors

Kumar, G.,White, S.W. (deposition date: 2015-08-07, release date: 2016-03-23, Last modification date: 2023-09-27)

• Primary citation: Song, M.S.,Kumar, G.,Shadrick, W.R.,Zhou, W.,Jeevan, T.,Li, Z.,Slavish, P.J.,Fabrizio, T.P.,Yoon, S.W.,Webb, T.R.,Webby, R.J.,White, S.W.; Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.; Proc. Natl. Acad. Sci. U.S.A., 113:3669-3674, 2016; PubMed: 26976575; DOI: 10.1073/pnas.1519772113

Experimental method

X-RAY DIFFRACTION (2.08 Å)