5D3Y
Crystal Structure of the P-Rex1 PH domain with Inositol-(1,3,4,5)-Tetrakisphosphate Bound
Summary for 5D3Y
Entry DOI | 10.2210/pdb5d3y/pdb |
Related | 5D27 5D3Z |
Descriptor | Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE (3 entities in total) |
Functional Keywords | pleckstrin homology domain, beta sandwich, phosphatidylinositol-binding, lipid binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 39574.06 |
Authors | Cash, J.N.,Tesmer, J.J.G. (deposition date: 2015-08-06, release date: 2016-04-20, Last modification date: 2023-09-27) |
Primary citation | Cash, J.N.,Davis, E.M.,Tesmer, J.J. Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3. Structure, 24:730-740, 2016 Cited by PubMed: 27150042DOI: 10.1016/j.str.2016.02.022 PDB entries with the same primary citation |
Experimental method |
Structure validation
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