5D3Y
Crystal Structure of the P-Rex1 PH domain with Inositol-(1,3,4,5)-Tetrakisphosphate Bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein | polymer | 167 | 19287.0 | 2 | UniProt (Q8TCU6) Pfam (PF22697) | Homo sapiens (Human) | PtdIns(3,4,5)-dependent Rac exchanger 1 |
| 2 | C, D (A, B) | INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE | non-polymer | 500.1 | 2 | Chemie (4IP) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 247 | Chemie (HOH) |
Sequence modifications
A, B: 245 - 408 (UniProt: Q8TCU6)
| PDB | External Database | Details |
|---|---|---|
| Gly 242 | - | expression tag |
| Glu 243 | - | expression tag |
| Phe 244 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38573.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1000.1 | |
| All* | Total formula weight | 39574.1 |
