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5D3Y

Crystal Structure of the P-Rex1 PH domain with Inositol-(1,3,4,5)-Tetrakisphosphate Bound

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BPhosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 proteinpolymer16719287.02UniProt (Q8TCU6)
Pfam (PF22697)
In PDB
Homo sapiens (Human)PtdIns(3,4,5)-dependent Rac exchanger 1
2A, BINOSITOL-(1,3,4,5)-TETRAKISPHOSPHATEnon-polymer500.12Chemie (4IP)
3waterwater18.0247Chemie (HOH)
Sequence modifications
A, B: 245 - 408 (UniProt: Q8TCU6)
PDBExternal DatabaseDetails
Gly 242-expression tag
Glu 243-expression tag
Phe 244-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight38573.9
Non-Polymers*Number of molecules2
Total formula weight1000.1
All*Total formula weight39574.1
*Water molecules are not included.

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PDB entries from 2024-08-14

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