5CZ2

Crystal structure of a two-domain fragment of MMTV integrase

Summary for 5CZ2

Entry DOI	10.2210/pdb5cz2/pdb
Descriptor	Pol polyprotein, MAGNESIUM ION, ZINC ION (3 entities in total)
Functional Keywords	integrase, pol, retrovirus, amino terminal domain, catalytic core domain, zinc binding, hydrolase
Biological source	Mouse mammary tumor virus (strain BR6) (MMTV)
Total number of polymer chains	12
Total formula weight	286955.76
Authors	Cook, N.,Ballandras-Colas, A.,Engelman, A.,Cherepanov, P. (deposition date: 2015-07-31, release date: 2016-02-17, Last modification date: 2024-01-10)
Primary citation	Ballandras-Colas, A.,Brown, M.,Cook, N.J.,Dewdney, T.G.,Demeler, B.,Cherepanov, P.,Lyumkis, D.,Engelman, A.N. Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function. Nature, 530:358-361, 2016 Cited by PubMed: 26887496 DOI: 10.1038/nature16955 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.72 Å)

Structure validation