5CUU

Crystal structure of Trypanosoma cruzi Vacuolar Soluble Pyrophosphatases in complex with bisphosphonate inhibitor BPH-1260

Summary for 5CUU

• Entry DOI: 10.2210/pdb5cuu/pdb
• Related: 5cuv 5cux 5cuy
• Descriptor: Acidocalcisomal pyrophosphatase, D-MALATE, 1-butyl-3-(2-hydroxy-2,2-diphosphonoethyl)-1H-imidazol-3-ium, ... (5 entities in total)
• Functional Keywords: substrate binding, acidocalcisomal pyrophosphatase, inhibitor, metal binding protein
• Biological source: Trypanosoma cruzi
• Total number of polymer chains: 2
• Total formula weight: 96939.06

Authors

Liu, W.D.,Yang, Y.Y.,Ko, T.P.,Zheng, Y.Y.,Chen, C.C.,Guo, R.T. (deposition date: 2015-07-25, release date: 2016-03-02, Last modification date: 2023-11-08)

• Primary citation: Yang, Y.Y.,Ko, T.P.,Zheng, Y.Y.,Liu, W.D.,Chen, C.C.,Guo, R.T.; Crystal structure of Trypanosoma cruzi protein in complex with ligand; Acs Chem.Biol., 2016

Experimental method

X-RAY DIFFRACTION (2.96 Å)