5CS2
Crystal structure of Plasmodium falciparum diadenosine triphosphate hydrolase in complex with Cyclomarin A
Summary for 5CS2
Entry DOI | 10.2210/pdb5cs2/pdb |
Descriptor | Histidine triad protein, Cyclomarin A, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | cyclomarin a, diadenosine triphosphate hydrolase, anti-plasmodial activity, malaria, plasmodium falciparum, hydrolase |
Biological source | Plasmodium falciparum 3D7 More |
Total number of polymer chains | 2 |
Total formula weight | 24744.58 |
Authors | Ostermann, N.,Schmitt, E.,Gerhartz, B.,Hinniger, A.,Delmas, C. (deposition date: 2015-07-23, release date: 2015-10-28, Last modification date: 2024-01-10) |
Primary citation | Burstner, N.,Roggo, S.,Ostermann, N.,Blank, J.,Delmas, C.,Freuler, F.,Gerhartz, B.,Hinniger, A.,Hoepfner, D.,Liechty, B.,Mihalic, M.,Murphy, J.,Pistorius, D.,Rottmann, M.,Thomas, J.R.,Schirle, M.,Schmitt, E.K. Gift from Nature: Cyclomarin A Kills Mycobacteria and Malaria Parasites by Distinct Modes of Action. Chembiochem, 16:2433-2436, 2015 Cited by PubMed: 26472355DOI: 10.1002/cbic.201500472 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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