5CQP

GTB mutant with mercury - E303Q

Summary for 5CQP

Entry DOI	10.2210/pdb5cqp/pdb
Related	5CMF 5CMG 5CMH 5CMI 5CMJ 5CQL 5CQM 5CQN 5CQO
Descriptor	Histo-blood group ABO system transferase, MERCURY (II) ION (3 entities in total)
Functional Keywords	human abo(h) blood group system, glycosyltransferase, double turn motif, catalytic domain, transferase
Biological source	Homo sapiens (Human)
Cellular location	Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P16442
Total number of polymer chains	1
Total formula weight	35216.05
Authors	Gagnon, S.M.L.,Blackler, R.J. (deposition date: 2015-07-21, release date: 2016-10-26, Last modification date: 2023-09-27)
Primary citation	Blackler, R.J.,Gagnon, S.M.,Polakowski, R.,Rose, N.L.,Zheng, R.B.,Letts, J.A.,Johal, A.R.,Schuman, B.,Borisova, S.N.,Palcic, M.M.,Evans, S.V. Glycosyltransfer in mutants of putative catalytic residue Glu303 of the human ABO(H) A and B blood group glycosyltransferases GTA and GTB proceeds through a labile active site. Glycobiology, 27:370-380, 2017 Cited by PubMed: 27979997 DOI: 10.1093/glycob/cww117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.83 Å)

Structure validation