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5CQ6

Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) in complex with 2,6-Pyridinedicarboxylic acid (SGC - Diamond I04-1 fragment screening)

Summary for 5CQ6
Entry DOI10.2210/pdb5cq6/pdb
DescriptorBromodomain adjacent to zinc finger domain protein 2B, 1,2-ETHANEDIOL, PYRIDINE-2,6-DICARBOXYLIC ACID, ... (4 entities in total)
Functional Keywordsstructural genomics, structural genomics consortium, sgc, transcription
Biological sourceHomo sapiens (Human)
Cellular locationNucleus : Q9UIF8
Total number of polymer chains1
Total formula weight14515.50
Authors
Primary citationBradley, A.,Pearce, N.,Krojer, T.,Ng, J.,Talon, R.,Vollmar, M.,Jose, B.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,Knapp, S.,Structural Genomics Consortium (SGC)
Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with 2,6-Pyridinedicarboxylic acid (SGC - Diamond I04-1 fragment screening)
To be published,
Experimental method
X-RAY DIFFRACTION (1.97 Å)
Structure validation

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PDB entries from 2024-04-17

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