5CKS

DAHP (3-deoxy-D-arabinoheptulosonate-7-phosphate) Synthase in complex with DAHP Oxime.

5CKS の概要

• エントリーDOI: 10.2210/pdb5cks/pdb
• 分子名称: Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive, beta-D-galactopyranose, DAHP Oxime, ... (4 entities in total)
• 機能のキーワード: dahp synthase, inhibitor, complex, transition state mimic, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Escherichia coli (strain K12)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 153613.01

構造登録者

Berti, P.,Junop, M.,Balachandran, N. (登録日: 2015-07-15, 公開日: 2016-08-10, 最終更新日: 2023-09-27)

• 主引用文献: Balachandran, N.,Heimhalt, M.,Liuni, P.,To, F.,Wilson, D.J.,Junop, M.S.,Berti, P.J.; Potent Inhibition of 3-Deoxy-d-arabinoheptulosonate-7-phosphate (DAHP) Synthase by DAHP Oxime, a Phosphate Group Mimic.; Biochemistry, 55:6617-6629, 2016; PubMed: 27933795; DOI: 10.1021/acs.biochem.6b00930

実験手法

X-RAY DIFFRACTION (2.1181 Å)