5CKR

Crystal Structure of MraY in complex with Muraymycin D2

5CKR の概要

• エントリーDOI: 10.2210/pdb5ckr/pdb
• 分子名称: Phospho-N-acetylmuramoyl-pentapeptide-transferase, Muraymycin D2 (3 entities in total)
• 機能のキーワード: alpha-helical, pnpt superfamily, phospho-murnac-pentapeptide translocase, membrane protein, bacterial cell wall, synthesis, natural product inhibitor, transferase-antibiotic complex, transferase/antibiotic
• 由来する生物種: Aquifex aeolicus (strain VF5)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 41870.63

構造登録者

Lee, S.Y.,Chung, B.C.,Mashalidis, E.H.,Tanino, T.,Kim, M.,Hong, J.,Ichikawa, S. (登録日: 2015-07-15, 公開日: 2016-03-02, 最終更新日: 2023-09-27)

• 主引用文献: Chung, B.C.,Mashalidis, E.H.,Tanino, T.,Kim, M.,Matsuda, A.,Hong, J.,Ichikawa, S.,Lee, S.Y.; Structural insights into inhibition of lipid I production in bacterial cell wall synthesis.; Nature, 533:557-560, 2016; PubMed: 27088606; DOI: 10.1038/nature17636

実験手法

X-RAY DIFFRACTION (2.95 Å)