5CIY

Structural basis of the recognition of H3K36me3 by DNMT3B PWWP domain

5CIY の概要

• エントリーDOI: 10.2210/pdb5ciy/pdb
• 分子名称: Modification methylase HhaI, DNA (5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*(3DR)P*GP*CP*AP*TP*GP*G)-3'), ... (6 entities in total)
• 機能のキーワード: cg-specificity, cpg sequence, c5-methylcytosine, nucleotide flipping, s-adenosyl-l-homocysteine, complex (methyltransferase- dna), transferase-dna complex, transferase/dna
• 由来する生物種: Haemophilus parahaemolyticus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 45412.82

構造登録者

Rondelet, G.,DAL MASO, T.,Willems, L.,Wouters, J. (登録日: 2015-07-13, 公開日: 2016-03-30, 最終更新日: 2024-01-10)

• 主引用文献: Rondelet, G.,Dal Maso, T.,Willems, L.,Wouters, J.; Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B.; J.Struct.Biol., 194:357-367, 2016; PubMed: 26993463; DOI: 10.1016/j.jsb.2016.03.013

実験手法

X-RAY DIFFRACTION (1.594 Å)