5CFB

Crystal Structure of Human Glycine Receptor alpha-3 Bound to Strychnine

Summary for 5CFB

Entry DOI	10.2210/pdb5cfb/pdb
Descriptor	Glycine receptor subunit alpha-3,Glycine receptor subunit alpha-3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, STRYCHNINE, ... (4 entities in total)
Functional Keywords	ligand-gated ion channel, neurotransmitter receptor, membrane protein, cys-loop receptor, transport protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	5
Total formula weight	212471.50
Authors	Shaffer, P.L.,Huang, X.,Chen, H. (deposition date: 2015-07-08, release date: 2015-09-30, Last modification date: 2023-09-27)
Primary citation	Huang, X.,Chen, H.,Michelsen, K.,Schneider, S.,Shaffer, P.L. Crystal structure of human glycine receptor-alpha 3 bound to antagonist strychnine. Nature, 526:277-280, 2015 Cited by PubMed: 26416729 DOI: 10.1038/nature14972 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.04 Å)

Structure validation