5CFB
Crystal Structure of Human Glycine Receptor alpha-3 Bound to Strychnine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Glycine receptor subunit alpha-3,Glycine receptor subunit alpha-3 | polymer | 362 | 41857.4 | 5 | UniProt (O75311) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (Human) | |
| 2 | F, G (F, G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | H, K, L, M, N (A, B, C, D, E) | STRYCHNINE | non-polymer | 334.4 | 5 | Chemie (SY9) PubChem (16757746) PubChem (16759292) PubChem (16760012) PubChem (5304) PubChem (121457) PubChem (23423987) PubChem (23636622) PubChem (3035321) PubChem (24011700) PubChem (25022186) PubChem (441071) PubChem (44135720) PubChem (54235484) PubChem (3037422) PubChem (3083694) PubChem (51035301) PubChem (71057032) PubChem (71073285) PubChem (5321532) PubChem (68315627) PubChem (74892805) PubChem (75539564) PubChem (5979) PubChem (6604670) PubChem (11336581) PubChem (3246505) PubChem (12359078) PubChem (98049553) PubChem (100078880) PubChem (98049551) PubChem (5702135) PubChem (5705187) PubChem (9840646) PubChem (9997016) PubChem (133611800) PubChem (124352578) PubChem (124389223) PubChem (124803013) PubChem (134814445) PubChem (134944247) PubChem (142877741) PubChem (149063339) PubChem (155935641) PubChem (162987392) PubChem (162987393) PubChem (162987394) PubChem (162987395) PubChem (162987396) PubChem (173470783) | |||
| 4 | I, J, O (A, B, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence modifications
A, B, C, D, E: 1 - 309 (UniProt: O75311)
A, B, C, D, E: 313 - 354 (UniProt: O75311)
A, B, C, D, E: 313 - 354 (UniProt: O75311)
| PDB | External Database | Details |
|---|---|---|
| Ala 310 | - | linker |
| Gly 311 | - | linker |
| Thr 312 | - | linker |
| Trp 355 | - | expression tag |
| Ser 356 | - | expression tag |
| His 357 | - | expression tag |
| Pro 358 | - | expression tag |
| Gln 359 | - | expression tag |
| Phe 360 | - | expression tag |
| Glu 361 | - | expression tag |
| Lys 362 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 209287.0 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2335.7 | |
| All* | Total formula weight | 212471.5 |
